Thursday, July 22, 2021

Another New Study Confirms: Legalizing Cannabis Not A Disaster After All

Yet another study confirms what we have known all along:  legalization of recreational cannabis was NOT a disaster after all.  The study found that legalization at the state level was NOT associated with any increases in drug treatment admissions, violent crime, or overdose deaths, and in some cases even appeared to have the opposite effect.  These findings dovetail with other recent studies as well, and we are really not surprised.  So much for the gateway drug theory, Reefer Madness, and other tired, old perennial Chicken Little predictions from the prohibitionists.

Additionally, just days earlier, another tired, old myth bit the dust as well.  Another new study finds no link between cannabis use and the stereotypical "amotivational syndrome" after controlling for confounders.  This particular study followed 14-17 year olds for a period of two years and did not find such a correlation, which is notable since numerous previous studies of the matter have generally failed to find such effects in adults but occasionally succeeded when looking specifically at adolescents.  So the fact that they could not detect such effects in that age group implies that such effects, if they do occur, are relatively rare and most likely confined to the small minority of very-heavy and ultra-heavy users and/or those who began using cannabis even earlier in life still.  And it thoroughly puts the lie to the fearmongers' claim that legalization would supposedly result in a nation of "orange-lipped couch-potato" zombies whose only semblance of motivation is the acquisition of their next hit.

And yet another myth debunked as well:  cannabis use does NOT appear to be independently linked to increased risk of stroke in young adults after adjusting for confounders such as tobacco use, according to another new study.  While previous studies on the matter have yielded inconsistent results, the prohibitionists of course luuurrrrved to spin such studies to their advantage.

Thus, no good reason not to fully legalize cannabis for everyone over 18 nationwide yesterday, and treat it no more stringently than alcohol or tobacco.  Period.

To anyone reading this who still opposes legalization, because reasons, we have a question for you: How does it feel to be on the wrong side of history?  Because we wouldn't know anything about that.

Thursday, May 27, 2021

Have A Safe And Happy Memorial Day Weekend

This coming Monday, May 31, is Memorial Day, often known as the unofficial first day of summer and National BBQ Day.  But let's remember what it really is--a day to honor all of the men and women of our armed forces who made the ultimate sacrifice for our country, past and present.  And that of course includes all of those who died serving our country before they were legally old enough to drink.  Let us all take a moment of silence to honor them.

As for Candy Lightner, the ageist turncoat founder of MADD who had the chutzpah and hubris to go on national TV in 2008 and publicly insult our troops, may her name and memory be forever blotted out. 

And as always, arrive alive, don't drink and drive.  It's just not worth it, period.  And it's very simple to prevent.  If you plan to drive, don't drink, and if you plan to drink, don't drive.  It's not rocket science.   Designate a sober driver, call a cab or rideshare, crash on the couch, or even walk if you have to.  Or don't drink--nobody's got a gun to your head.

Wednesday, May 19, 2021

"No Safe Level" Is A Red Flag For Junk Science

According to a wise man named Paracelsus (essentially the Western world's first toxicologist) long ago, it is the dose that makes the poison.  Anything (even water) can be poisonous in a high enough quantity, and conversely there is, practically speaking, a safe level for everything.  It is all a matter of degree.  So why, when it comes to things like alcohol, do the "experts" seem to lose all common sense?

Take the latest study of alcohol and the brain at Oxford, for example.  This one claims that there is no safe level of alcohol for the brain, that is, any amount will cause damage.  The observational study, which notably has not even been peer-reviewed yet, finds a negative linear correlation between alcohol drinking volume and the volume of gray matter (as well as white matter) in brain scans, even after controlling for every confounder they could think of.  While it is known that excessive drinking can damage the brain, the shocker here seems to have more to do with much lower levels of drinking previously thought to be safe.

I bet the reader can quickly spot the problem here.  If not, here it goes.  A closer look at the data shows that, given how small the overall effect size is, with alcohol explaining only 0.8% of the variance in gray matter, combined with the tendency of people (especially heavier drinkers) to undercount their drinks, the apparent harmful effects of light to moderate drinking may very well be spurious at the lower end of the curve even if likely genuine towards the higher end.  That, and the lack of peer review of course.

They also found an additive effect of "binge" drinking over and above the effect of drinking volume alone, particularly for daily "binging", which was fairly strong and consistently statistically significant.  But given the rather wide confidence intervals, for less than daily "binge" drinking, it was not always statistically significant.  Given the typically fairly low definitions used for "binge" drinking, it would not be surprising that the confidence intervals are so wide.

It also appears from this study that people with hypertension (high blood pressure) and/or a high BMI are significantly more sensitive to the apparent adverse effects of alcohol than the average person for whatever reasons as well.  The interaction was not just additive, but multiplicative.  That will certainly require further study going forward. 

We are not in any way encouraging anyone to drink alcoholic beverages. But specious inferences should not cloud the issue either.

There is a safe level everything, even arsenic apparently.  So why would that not be true for alcohol?  Especially since our own bodies can actually produce a bit of it as a byproduct, believe it or not?

On the bright side, at least the study looked largely at older adults (age 40+) and did not indulge in the usual youth drinking panic routines.  Even if the observed effects are 100% true, that would of course mean that young people are not uniquely vulnerable to the adverse effects of alcohol on the brain.